99% Purity Glyx-13 Rapastinel Peptide CAS 117928-94-6

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: 117928-94-6
• Certification: ISO 9001
• State: Solid
• Purity: >99%
• Transport Package: 1kg/Bag
• Specification: 1kg/Bag
• Trademark: Lonwin
• Origin: China
• Production Capacity: 1000kg/Month

Product Description

Product Details : GLYX-13 /Rapastinel
CAS: 117928-94-6
MF: C18H31N5O6
Sequence:  Thr-Pro-Pro-Thr-NH2
Synonyms GLYX 13;L-ThreoninaMide, L-threonyl-L-prolyl-L-prolyl-;GLYX-13 trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate;Thr-Pro-Pro-Thr-NH2 trifluoroacetate;TPPT-amide trifluoroacetate;Rapastinel;GIYX-13
Purity: 99.0%
Appearance: White Powder
Test Method: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below-18° C. 

Rapastinel (GLYX-13) is a NMDA receptor modulator with glycine-site partial agonist properties. It is a robust cognitive enhancer and shows rapid and long-lasting antidepressant properties in both animal models and in humans.
 
Rapastinel was derived from a monoclonal antibody, B6B21, is a tetrapeptide (threonine-proline-proline-threonine-amide) obtained from amino acid sequence information obtained from sequencing one of the hypervariable regions of the light chain of B6B21. The in-vivo and in-vitro pharmacology of rapastinel was examined.

Product Application

Rapastinel was found to be a robust cognitive enhancer in a variety of learning and memory paradigms and shows marked antidepressant-like properties in multiple models including the forced swim (Porsolt), learned helplessness and chronic unpredictable stress.

Rapastinel's rapid-acting antidepressant properties appear to be mediated by its ability to activate NMDA receptors leading to enhancement in synaptic plasticity processes associated with learning and memory.

This is further substantiated by the increase in mature dendritic spines found 24 hrs after rapastinel treatment in both the rat dentate gyrus and layer five of the medial prefrontal cortex. Moreover, ex vivo LTP studies showed that the effects of rapastinel persisted at least two weeks post-dosing.

GLYX-13 Peptide Mode of Action:
1. Enhance mental intelligence;
2. Boost memory and leaning capabilities;
3. Improve brain power to solve problems and protect it from any chemical or physical injury;
4. Enhance motivation level;
5. Enhance the control of cortical/subcortical brain mechanism;
6. Improve sensory perception.

Packaging & Shipping

Welcome to contact us to get complete COA.
Shanghai Lonwin Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. 

We could give you: 
1.Best quality in your requirement 
2.Competitive price in China market 
3.Mature Technical support 
4.Professional logistic support 
All we want is win-win business. Send yr. inquiries, you will get it!

Storage:
keep container tightly closed in a dry and well-ventilated place.
Packing:25kgs/bag or 25kgs/drum

Weight	Packing
<25KG	By foil-alum bag/pap/bottle
≥25kg	Package: 25kg/drum/bag or as your request

Company Profile

Lonwin Chemical Industry Group is a company committed to the contract synthesis and production of Medicine Polypeptide, Beauty Polypeptide, Customized Polypeptide, and APIs. Our company holds ISO and REACH international certifications. We have OEM processing plants with decades of cooperation in Jiangsu, Anhui, and other regions, providing a more solid foundation for the customized production services of special chemicals.Currently, our products are widely sold in North America, Europe, Japan, South Korea, and the Middle East. Customers are highly satisfied with both our products and services.

To achieve sustainable and stable development, we have established close cooperative relationships with renowned universities and institutions in China. We regularly exchange information with them and collaborate on new technology R&D.Adhering to the business philosophy of "quality first, credit first, service first, creativity first", we are striving to meet the demands of customers worldwide. We sincerely welcome your visit and business cooperation and look forward to working with you to expand the international market together!

 

FAQ

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China. So you will be assured with Good Quality if you choose us. 

Q2: How do you treat quality complaint?
A: First of all, our QC department will do strict examination of our export products by HPLC, UV, GC,TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.

Q3: How to cooperate with us?
A: You can contact us for cooperation through the website contact information, or contact with the salesmen in our company. We will connect you about the specific detail via email. 

Q4: Do you Accept Sample Order
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q5: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q6: How long does it take to the goods arrived?
A: It is Depending on your location. For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS. For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7: Do you have any reshipment policy?
A: We have good after-sale service and re-shipment policy if the parcel  lose. Our long association with  our clients has brought great benefits. We always take the upmost care in the packaging of our products. Our clients will confirm this as even they struggle to find them without help at times. But in spite of our best efforts it is still possible  will seize a small number of packages. In this circumstance we promise reship free  to establish  long term relationship.